However, surface piercings of the perineum are easier to care for and much more common. In most cases, no serious cause is responsible. These may be used to fight infections of the anus caused by bacteria. It is not to be confused with Bunghole. The cause is unknown. Over-the-counter or prescription stool softeners can relieve these symptoms. Suspensory muscle Major duodenal papilla Minor duodenal papilla Duodenojejunal flexure Brunner's glands.